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Senior Scientist, CBID Cytometry

Company: Takeda Pharmaceutical
Location: Palisades Park
Posted on: November 18, 2021

Job Description:

By clicking the -Apply- button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's and . I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionSenior Scientist, CBID Cytometry Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Senior Scientist, CBID Cytometry in our Cambridge, MA office.At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.Here, you will be a vital contributor to our inspiring, bold mission.As a Senior Scientist, CBID Cytometry working on the Clinical Biomarkers team, you will be empowered to serve as the CBID resident cytometry workflow and assay expert, whose role includes: advising translational scientists on best practices and biomarker assays/technologies. -A typical day will include:POSITION OBJECTIVES:

  • Serve as the CBID resident cytometry workflow and assay expert, whose role includes: advising translational scientists on best practices and biomarker assays/technologies, as well as, investigating novel technologies for clinical readiness and implementing as necessary.
  • Contribute to the clinical development of novel therapeutics in Gastroenterology, Neuroscience, and Rare Disease that are currently in Phase I-Phase III clinical trials by developing traditional cytometry-based assays and novel technologies with external CROs.
  • Establish methodologies for routine analysis as well as advanced machine-based learning algorithms.POSITION ACCOUNTABILITIES:
    • As CBID cytometry subject matter expert, attend and participate in key program team meetings (e.g. clinical and translational subteams) and provide insight and support for flow cytometry, CyToF, spectral flow cytometry, cell sorting, and other cytometry-based assays.- You should be familiar with cytometry work flows from sample prep through to data generation and analysis.
    • Evaluate, select, and oversee external labs and vendors to ensure successful design and execution of clinical assays, including: validation, longitudinal performance, data quality, and timely delivery.
    • Analyze and interpret clinical cyometry-based biomarker data.- Develop and present biomarker results to CBID leadership team and program/clinical teams.
    • Collaborate with biomarker scientists to design experiments which leverage cytometry data to support clinical drug development.
    • Collaborate with individuals from other functions, e.g. computational biology, translational sciences, and modeling to further analyze and interpret data, especially in context with other clinical data.-
    • Lead development of innovative approaches to new assays based on emerging scientific insights, new technologies and/or program needs.
    • Other responsibilities include being current and leading scientific due diligence of cutting-edge technologies, establishing external partnerships as needed, building external bridges (e.g. scientific leaders, KOLs, academic partners, CROs, and health authorities), mentoring other scientists, and actively publishing/presenting in the external scientific community.
    • Success in this role will be evaluated by the ability to influence and inspire scientists in the organization, and to maintain a culture that encourages innovation, scientific rigor, and collaboration.EDUCATION, BEHAVIORAL COMPETENCIES AND SKILLS:
      • A PhD, MD, or MD/PhD in immunology, molecular biology, or related discipline with at least 5 years of relevant experience beyond post-doctoral training, including at least 2 years of industry experience.
      • Strong scientific background and experience with assay development and validation across technology platforms in cytometry, especially those that are clinically amenable.
      • Strong understanding of and experience in cytometry technologies and workflows.-
      • Experience with advanced analysis tools such as deep learning algorithms or AI and/or other technologies such as pathology/histology, genomics, etc a plus.
      • Disease knowledge and experience in gastroenterology, rare disease, or neuroscience a plus.
      • Experience with outsourcing and working with external partners to develop/transfer assays and to oversee data generation/analysis and delivery of high quality data within expected timelines.
      • Familiarity with clinical documents and processes, i.e. clinical protocols, informed consent forms, laboratory manuals, central lab logistics, etc.
      • Strong written and oral communication skills, ability to influence and inspire, takes initiative yet team-oriented and collaborative, and able to navigate and be effective in large matrixed environments.
      • Prior leadership and mentoring experience a plus.Takeda U.S. Vaccine Requirement:Absent an approved religious or medical reason, all US office-based and lab-based Takeda employees who work fully on-site or in a hybrid model (as determined by Takeda) must be fully vaccinated to work at a Takeda site or to engage with Takeda colleagues or anyone else on behalf of Takeda. US field-based employees must be fully vaccinated as a condition of employment, absent an approved religious or medical reason. US employees who work at a Takeda manufacturing facility, and those who work at a BioLife center or BioLife lab, may be subject to different guidelines. If you are contacted by a Takeda recruiter about your job application, we encourage you to seek more information on the applicable guidelines for the Business Unit/Function to which you have applied.This job posting exclude Colorado applicants.WHAT TAKEDA CAN OFFER YOU:
        • 401(k) with company match and Annual Retirement Contribution Plan
        • Tuition reimbursement Company match of charitable contributions
        • Health & Wellness programs including onsite flu shots and health screenings
        • Generous time off for vacation and the option to purchase additional vacation days
        • Community Outreach ProgramsEmpowering Our People to ShineDiscover more at takedajobs.comNo Phone Calls or Recruiters Please.*RM-LIEEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsBoston, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

Keywords: Takeda Pharmaceutical, Tenafly , Senior Scientist, CBID Cytometry, Other , Palisades Park, New Jersey

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